Moreover, mice in which the γ2 subunit of GABAA receptor (Gabrg2) was homozygously mutated (F77I) (genotype: Gabrg2F77I/F77I), causing a loss of interaction with ACBP/DBI,24 were relatively resistant to Myc/Ctnnb1-induced HCC as well (Figures 3E–3H and S6B). This evidence concerns the gene MYC and hepatocellular carcinoma.