Multisystem anomaliesSuspected skeletal dysplasia (excluding confirmed FGFR3/2 variant)Large bilateral echogenic kidneys with normal bladderMajor CNS anomaly (excluding NTD)Multiple contractures (excluding isolated bilateral talipes)NT > 6.5 mm plus another anomalyIsolated NIHF detected at or after routine 18–20‐week scan in second or third trimester, defined as fluid/edema in at least two compartmentsAnomaly of corpus callosumSGA (all biometry < 3rd centile) and no evidence of placental insufficiencyIsolated SLB (all < 3rd centile) and no evidence of placental insufficiency. Here, FGFR3 is linked to neural tube defect.