While many of the genes associated with ALCL were expressed in the Donor 4 replicates, previously mentioned genes, TNFRSF8, STAT3, GZMB, and PRF1 stood out as upregulated in the resurgent replicate 2 HIV/GFP+ cells and high-grade T cell lymphoma samples. Here, PRF1 is linked to T-cell non-Hodgkin lymphoma.