Mutations in human and mouse Myo15A cause DFNB3-associated deafness and vestibular dysfunction (Probst et al., 1998; Wang et al., 1998; Anderson et al., 2000; Rehman et al., 2016), with defects in stereocilia growth and actin bundle regulation (Belyantseva et al., 2005; Delprat et al., 2005; Fang et al., 2015; Rehman et al., 2016). The gene discussed is MYO15A; the disease is deafness.