The spatial feature plot of CreERT expression in different regions of HF and skin is shown in Figure 4C. The dot plot in Figure 4D illustrates the expression of CreERT and Krox20, along with other IFE markers (K14, K15, K1, Sca1/Ly6a, Thy1, and loricrin), Lrig1 (a marker of the upper HF), and Nestin, (11, 12) in different clusters. This evidence concerns the gene LY6S and hydrops fetalis.