Similar to human patients with PID, mice with point mutations in Hem1 mice were severely immunodeficient, and were characterized by dwarfism, hepatomegaly, microcytic anemia, extramedullary hematopoiesis, reduced T and B cell development, altered T cell cytokine production, impaired phagocytosis, and impaired neutrophil migration (9–11). The gene discussed is NCKAP1L; the disease is pelvic inflammatory disease.