STING1 and neoplasm: Administration of MSA-2 led to complete tumor regression in the subset of mice bearing KP1 TAS1440 tumors (n = 5 of 12), but not in the mice bearing KP1 DMSO (n = 0 of 10) or KP1 TAS1440 plus GSI (n = 0 of 10) tumors (χ2 value, P = 0.04) (Figure 8B), suggesting that only Notch-driven tumors are sensitive to STING agonism.