For instance, a study on Pongamia pinnata extract against skin cancer demonstrated that MD simulations were essential in verifying the stability of the complexes EGF-Pazopanib, EGFR-Pongachromene, and ERBB2-Vitexin up to 100 ns without any major fluctuation (Navyatha Karamala et al. 2025). The gene discussed is EGFR; the disease is skin neoplasm.