,29,33,43 Previous studies have demonstrated that DJ-1/Nrf2 signaling is involved in the corneal endothelium, particularly in type 2 diabetic mice, where DJ-1 downregulation increases the susceptibility of corneal endothelial cells to oxidative damage induced by ultraviolet A.44–46 However, the impact of DJ-1 downregulation on the corneal epithelium remains unclear. The gene discussed is PARK7; the disease is type 2 diabetes mellitus.