TP53 and glioblastoma: To identify potential factors that are highly expressed in TAMs and might mediate the GBM-TAM bidirectional interaction, we analyzed RNA-Seq data of GBM-associated BMDMs and microglia isolated from tumors of GL261 and RCAS (a genetically engineered mouse model with Pdgfb induction and Trp53 knockdown) models (33).