Within the tumor-associated myeloid cells, CD11b+CD45hiCD68+ macrophages and CD11b+CD45loCX3CR1+ microglia exhibited higher GPNMB expression compared with that of CD11b+CD45hiCD11c+ DCs, CD11b+CD68+Ly6GloLy6Chi monocytic IMCs, and CD11b+CD68+Ly6GhiLy6Clo polymorphonuclear IMCs (Figure 1, H–K). Here, GPNMB is linked to neoplasm.