Next, we used the Brain Tumor Immune Micro Environment (TIME) dataset to analyze the expression levels of these 5 genes in CD45– GBM cells and tumor-associated immune cells (e.g., BMDMs, microglia, neutrophils, CD4+ T cells, and CD8+ T cells) isolated from human GBM tumors (34). The gene discussed is CD8A; the disease is glioblastoma.