PLA2G2A and benign prostatic hyperplasia: Phospholipase A2 (PLA2), a key enzyme in glycerophospholipid catabolism, hydrolyzes glycerophospholipids to release bioactive mediators such as arachidonic acid, thereby modulating inflammatory responses and cellular proliferation in BPH (Hayashi et al., 2022; Turnaev et al., 2022).