Studies have shown that the increase of Hcy level is closely related to the occurrence and development of hypertension: high Hcy activates angiotensin converting enzyme by inhibiting the production of endogenous hydrogen sulfide in the body, produces angiotensin II and acts on angiotensin type 1 receptor, thus leading to a series of pathological processes such as the increase of blood pressure and vascular proliferation (15, 16). The gene discussed is ACE; the disease is hypertensive disorder.