PPAR-γ2 [the dominant isoform responsible for NASH progression (16, 17), 12,805,374, 17,704,301] expression in C2 and D2 groups was significantly lower than in C1 group (p < 0.001 and p < 0.05, respectively). The gene discussed is PPARG; the disease is metabolic dysfunction-associated steatohepatitis.