To identify hub genes with significant differences between HF patients and non-HF patients post-MI, we employed the SVM-RFE algorithm to select 10 candidate genes (DZIP3, HIVEP2, ZNF366, CYLD, SNORD28, GPER1, E2F5, LHFPL2, ADAMTS2 and ST14) (Figure 2A). The gene discussed is CYLD; the disease is hydrops fetalis.