CD4 and experimental autoimmune encephalomyelitis: The presence of CD62l on FoxP3 cells identifies a particularly immunosuppressive cell type in settings of experimental autoimmune encephalomyelitis (29) and graft-vs.-host disease following allogeneic bone marrow transplant (30), and may have contributed to the benefit of DAC in allografts of CD4 + FoxP3+ Treg depleted hosts.