CD8A and neoplasm: Brown et al. showed that CD8 + T cells were higher at the tumor injection site than at a more distal tumor biopsy site after intracavitary injection,10 Choi et al. showed that the percentage of CAR-T cells in the blood was consistently lower (0%–2%) than in CSF (~70%) after intraventricular injection,7 and Bagley et al. showed that initial expansion of CAR-T cells was higher in CSF than in peripheral blood of all patients.9