(39) demonstrated that adipocytes co-cultured with melanoma cells could exhibit fibroblast characteristics and secrete higher levels of IL-6 and serpine1, while producing less C-C motif chemokine ligand 2 (CCL2), chemokine (C-X-C motif) ligand 1 (CXCL1), and angiogenic molecules. Here, CXCL1 is linked to melanoma.