Also, miRNA-29 family members (hsa-mir-29a-3p; -29b-3p and -29c-3p) control immune responses by targeting interferon-gamma and other pro-inflammatory cytokines, suggesting its involvement interferon-gamma release during T-cell and NK-cell responses in the immunopathogenesis of TB-IRS (15, 42). The gene discussed is IFNG; the disease is tuberculosis.