reported that miR-155–/– conventional KO mice given a single dose of BLM developed exacerbated lung fibrosis, increased collagen deposition, TGF-β production, and activation of profibrotic macrophages by dysregulation of liver X receptor (LXR)α in lung fibroblasts and macrophages (72). The gene discussed is NR1H3; the disease is pulmonary fibrosis.