ITGAX and pulmonary fibrosis: In a bleomycin (BLM)-induced PF model, we show that miRNA loss, driven by CD11c-Cre-mediated Dicer deletion, induces significant changes in the transcriptomic profiles and signaling pathways of tissue-resident AMs (TR-AMs) and monocyte-derived AMs (Mo-AMs) during fibrogenesis, contributing to a reduction in the severity of lung fibrosis.