Univariate Cox regression analysis revealed that high expression of PKNOX1 was a prognostic risk factor for OS in patients with GBMLGG(Glioma), LIHC, MESO, UVM, LGG, ACC, SARC, and KIRP (Figure 4H); it was a prognostic risk factor for DSS in patients with GBMLGG, LIHC, MESO, UVM, LGG, ACC, SARC, KIRP, and GBM (Figure 4I); and it was a prognostic risk factor for PFI in patients with GBMLGG, LIHC, UVM, LGG, ACC, PRAD, and KIRP (Figure 4J). Here, PKNOX1 is linked to central nervous system cancer.