The results revealed that patients with advanced clinical T stage (T3&T4) showed higher levels of PKNOX1 expression in ESCA, KIPAN(Pan-kidney cohort), STAD, PRAD and LIHC tumors (Figure 4A), and patients with advanced pathological G stage (G3/G4) showed higher levels of PKNOX1 expression in HNSC, KIRC, KIPAN, LIHC, LGG, and PAAD tumors (Figures 4B–G). The gene discussed is PKNOX1; the disease is pancreatic adenocarcinoma.