We used R language to perform Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis and found that PKNOX1 was involved mainly in the intercellular adhesion junction pathway, the cell cycle pathway, the ERBB signalling pathway, the NOTCH signalling pathway and the WNT signalling pathway (Figure 9M), indicating that PKNOX1 may promote tumor occurrence and development by promoting tumor proliferation, migration and invasion. The gene discussed is EGFR; the disease is neoplasm.