Compared with adjacent normal tissues, in addition to the above 9 tumor types expressing higher levels of PKNOX1, PKNOX1 was also highly expressed in ACC(adrenocortical cancer), DLBC(diffuse large B-cell lymphoma), OV(ovarian serous cystadenocarcinoma), PAAD(pancreatic adenocarcinoma), UCEC (uterine corpus endometrioid carcinoma), GBM (glioblastoma multiforme),PCPG (pheochromocytoma&paraganglioma),UCS (uterine carcinosarcoma), LAML (acute myeloid leukemia), LGG (brain lower grade glioma), SARC (sarcoma), SKCM (skin cutaneous melanoma), and THYM (thymoma) (Figure 1B). Here, PKNOX1 is linked to hereditary pheochromocytoma-paraganglioma.