PKNOX1 was highly expressed in 22 tumor tissues, including BRCA, CHOL, LIHC, LUAD, LUSC, STAD, COAD, ACC, and SKCM, which was consistent with the reported results for gastric adenocarcinoma and non-small cell carcinoma (17, 18) and with the results of our immunohistochemical analysis in liver cancer, lung cancer, gastric cancer, and intestinal cancer. The gene discussed is PKNOX1; the disease is neoplasm.