BCAT2 and pancreatic ductal adenocarcinoma: In a pancreatic ductal adenocarcinoma (PDAC) study, SIRT4 deacetylated branched‐chain amino acid transaminase 2 (BCAT2) at lysine 44 (K44), and BCAT2 was stabilized by SIRT4 deacetylation, thereby promoting catabolism of branched‐chain amino acids,40 whereas methylcrotonyl coenzyme A carboxylase complex (MCCC) was previously shown to interact with SIRT4 and was considered a putative substrate for SIRT4.39