As such, many cystic fibrosis (CF) patients could develop cystic fibrosis-related diabetes (CFRD) exhibiting insulin insufficiency, a significant extra-pulmonary comorbidity associated with the CF transmembrane conductance regulator (CFTR) (Guo et al., 2014; Koivula et al., 2016). This evidence concerns the gene CFTR and cystic fibrosis-related diabetes.