The same was observed for LSS, with a significantly higher risk of lymphoma‐related death in pre‐treated dogs both when calculated from the start of CHOP (HR: 1.7; 95% CI: 1.3–2.3; p < 0.001; Figure 2) and from the start of steroid therapy (HR: 1.6; 95% CI: 1.2–2.1; p = 0.004). Here, DDIT3 is linked to lymphoma.