In ischemic stroke, we found that MPO, CALCRL, PPP5C, KTN1-AS1, CCR1, CTB-50L17.9, CCR9, ZNF362, ZIK1, ELP5, CKAP2, NUP88, and SEC16A show risk effects (OR > 1). The gene discussed is ELP5; the disease is ischemic stroke.