Furthermore, the correlation between the receptor molecular signals of PTN and TNF signalling pathways was assessed in tumour-infiltrating B cells, and we found that the positive correlations between the receptor molecular signal scores of PTN and the scores of the three TNF-associated signalling pathways were greater in IBC tumour-infiltrating B cells than in nIBC, with the receptor molecular signal scores of PTN correlating with the response to tumour necrosis factor having the highest correlation between them (Extended Data Fig. S9f). The gene discussed is TNF; the disease is neoplasm.