APOE and neoplasm: These results suggest that tumour-infiltrating myeloid cells as a whole exhibit a greater degree of suppression and that IBC tumour-infiltrating myeloid cells are predominantly CD163 + macrophages, whereas myeloid cells in nIBC tumours are predominantly primary APOE + macrophages, suggesting that IBC tumour-infiltrating myeloid cells have a greater state of immunosuppressive properties.