Univariate analysis showed that T2DM, HCV-MASLD, hypertriglyceridemia, hypo-HDL cholesterolemia, AST, ALT, ɤ-GTP, albumin, platelet count, FSG, HDL-C, AFP, LSM, FIB-4 index, aMAP score, and FAST score were significantly associated with HCC development (Table 2). This evidence concerns the gene AFP and hypertriglyceridemia.