RNPC3 and neoplasm: Histological examination of the lungs 90 d after AdCre delivery revealed a significant reduction in the tumour area and the number of AAH lesions in cells harbouring recombined Rnpc3lox/lox;KrasG12D alleles, compared to cells containing Rnpc3+/+;KrasG12D alleles (Fig. EV2A–D).