TFF1 and gastric adenoma: To determine whether inducing loss of Rnpc3 expression in established gastric adenomas also reduced growth (compared to constitutive heterozygosity), we crossed mice carrying conditional Rnpc3lox alleles with Gp130F/F mice also carrying a Trefoil factor 1 (Tff1)-CreERT2 BAC transgene that confers tamoxifen (TMX)-inducible, gastric epithelium-selective, Cre recombinase activity (Thiem et al, 2016a).