Beyond its role in protein synthesis regulation, eEF2K activates clinically significant pathways, such as PI3K/AKT, cyclin D1, and c-Myc, which promote cancer cell proliferation, invasion, and tumor growth in various types of cancers, including triple-negative breast (TNBC) [36, 48, 49] lung [50], ovarian [38], and pancreatic cancer [37]. This evidence concerns the gene CCND1 and neoplasm.