The above DEGs were also related to oxidative stress (Hmgcs2, Drd5, and Slc4a11) (Fig. 1F) and synaptic function (Ddit4, Drd5, and Nptx1) (Fig. 1G), which may cause ND, such as AD and PD. The gene discussed is SLC4A11; the disease is Norrie disease.