HDAC3 and acute myeloid leukemia: To systematically elucidate the mechanism by which HDAC3 regulates mitochondrial oxidative stress homeostasis in BMSCs, we compared the sequencing data of shHDAC3-BMSCs with transcriptome data from patient-derived BMSCs (GSE92778) and AML cell co-culture-treated BMSCs (GSE45663) using Gene Set Enrichment Analysis (GSEA).