FOXA1 and metastatic malignant neoplasm in the lymph nodes: Lower FOXA1 expression was primarily linked to UDC and advanced stages, marked by higher T stage (tumor sizes, T3-T4), N stage (lymph node metastasis, N2-N3), M stage (distant metastasis, M1) and clinical stage (III-IV) (Fig. 1C, D; Table 2).