Over a median follow‐up period of 9 years, participants with any CHIP (variant allele fraction [VAF] ≥ 2%) exhibited a significantly elevated risk of developing incident or recurrent AF compared to those in the non‐CHIP group (hazard ratio [HR] = 1.12; 95% confidence interval [CI] = [0.07 to 1.17], p < 0.0001; I2 = 3%, heterogeneity p = 0.38). This evidence concerns the gene STUB1 and atrial fibrillation.