To determine whether the IFN-I-mediated expression of Rnf213 was specific to A. baumannii infection, we examined Rnf213 expression in WT and Ifnar–/– BMDMs and MSFs in response to infections with multiple pathogens and multiple stimuli via real-time quantitative polymerase chain reaction (RT‒qPCR) analysis. This evidence concerns the gene RNF213 and infection.