CD4 and myasthenia gravis: Comparative profiling revealed significant disparities in lymphocyte subset proportions between MG patients and healthy controls (Fig 5a; S5 Table).Computational deconvolution revealed elevated naive B cell infiltration coupled with paradoxical depletion of antibody-secreting plasma cells and memory CD4+ T cell subsets (resting/activated) in MG patients versus controls (Fig 5b), implying multifactorial impairment of adaptive immunity, potentially involving defective B cell maturation and T cell memory formation.