Receiving ticagrelor modulated ferroptosis in FCA-induced arthritis rats via upregulation of SLC7A11 (F(1, 20) = F(1, 20) = 5152, p < 0.0001, η2 = 0.16) GPX4 (F(1, 20) = 2150, p < 0.0001, η2 = 0.15) and FTH1 (F(1, 20) = 6806, p < 0.0001, η2 = 0.16) content to reach 9.80, 2.20, and 8.49-folds compared to the AIA group rats. The gene discussed is FTH1; the disease is arthritic joint disease.