The proportion of RFP+ cells within the GFP+ leukemic cell population significantly increased in the AE9a‐Ddit4−/−‐Hoxa6 group, whereas it remained consistently low in the AE9a‐Ddit4−/−‐Vec group, indicating that the expression of Hoxa6 might confer a growth advantage in AE9a‐Ddit4−/− leukemia cells. The gene discussed is HOXA6; the disease is leukemia.