High EGFR expressing tumour cells were shown to have elevated epithelial‐to‐immune interactions through (1) PTN (interacting with NCL on immune cells), (2) PLAU (interacting with PLAUR on macrophages), (3) ADM (interacting with CALCRL on pDCs) and (4) MDK (interacting with ITGA4 and ITGB1 on macrophages) (Figure 3G,H) – potentially facilitating pro‐tumourigenic microenvironment. This evidence concerns the gene MDK and neoplasm.