As EGFR expression was positively correlated with its genomic‐copy‐number in TCGA‐HNSC cohort (Figure S7B), to further elucidate the plausible mechanism of EGFR driven immune suppression, we have created and analysed an integrated gene expression atlas of 66,809 single cells from 55 oral cavity tumours (Figure 3A–E). This evidence concerns the gene EGFR and oral cavity neoplasm.