HTN3 and denture stomatitis: Denture stomatitis affects up to 60% of prosthesis usersdue tobiofilms mainly composed of Candida albicans and Streptococcus mutans, which persistthe treatments because of their resilient extracellular matrix (ECM).This study tested four proteins/peptideshistatin 3 (His3),histatin 5 (His5), DR9-RR14, and RR14on these mixed biofilmsgrown on acrylic resin.