CDH1 and Barrett esophagus: CDH1 has severely reduced or disorganized expression during BE dysplastic progression (reviewed by Kalatskaya (2016)) and an almost undetectable expression in poorly differentiated EAC (Darlavoix et al., 2009; Falkenback et al., 2008; Feith et al., 2004; Kalatskaya, 2016; Yao et al., 2021).