In contrast, TGF-β-3 expression, also normalized to GAPDH, was significantly elevated across tumor grades, increasing from 2.17 ± 0.42 in G2 to 4.54 ± 0.65 in G3 and 5.15 ± 1.09 in G4 (p < 0.05). Here, GAPDH is linked to neoplasm.