AKT1 and cancer: The phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) signaling pathway is a well-established biological process involving the regulation of diverse signalings such as apoptosis, metabolism, cell proliferation and growth, protein synthesis, transcription, glucose uptake, and aerobic glycolysis in cancer cells (Fresno Vara et al., 2004; Fruman et al., 2017).