The TIMER immune association module showed that HOXB6 and HOXB8 expression was positively correlated with the presence of immunosuppressive cell infiltrates such as myeloid-derived suppressor cells (MDSC) and tumor-associated fibroblasts (Fig. 7a, n = 179) in PDAC samples, further supporting an association between HOX gene expression and immune response in PDAC. The gene discussed is HOXB6; the disease is neoplasm.