Epigenetic regulation of CAMTA1 has been studied in various contexts, including cancer, where histone modifications have been shown to modulate CAMTA1 expression [122], and ischemic stroke, where CpGs in the promoter of CAMTA1 were found to be hypermethylated in peripheral blood from patients compared to controls, and correlated with gene expression [128]. The gene discussed is CAMTA1; the disease is ischemic stroke.