Some reports indicated that elevated levels of PD-L1 expression can be observed in DLBCL tumor cells compared with FL tumor cells [65], while other studies suggest that PD-L1 expression levels are typically low in B-cell NHL tumor cells, and can only be observed in some non-GCB subtypes of DLBCL [66–69]. The gene discussed is CD274; the disease is diffuse large B-cell lymphoma.