E-cadherin upregulation along with the expression of Snail 1, MMP9, NCAD, and vimentin, which was characteristic of mesenchymal cells, being significantly suppressed after TRIM47 reduced expression suggests that the TRIM47 silencing worsened the cell migration and invasion of thyroid carcinoma by ablating epithelial-mesenchymal transition (EMT). Here, VIM is linked to thyroid gland carcinoma.