Compared to HFD‐fed WT mice, HFD‐fed Nod1−/− mice exhibited increased lung inflammation, as evidenced by higher neutrophil MPO expression and activity (Figure 3a–d) and elevated secretion of the cytokines TNF‐α, IL‐1β, and IL‐6 (Figure 3g). The gene discussed is IL1B; the disease is inflammation.