Meanwhile, BIRC3 was negatively correlated with tumor purity (Rho = − 0.43, p = 2.85 × 10− 20, Fig. 2B) and positively correlated with dendritic cell infiltration (Rho = − 0.475, p = 6.47 × 10− 25, Fig. 2B), suggesting that BIRC3 is associated with GBM TME infiltration. The gene discussed is BIRC3; the disease is glioblastoma.