FGFR3 and urinary bladder carcinoma: We identified prominent negative associations of FGFR3 mutations (especially p.S249, p.Y375) with 11 immune and three stromal cell types in bladder cancer, suggesting FGFR3 may have a role in establishing an immunosuppressive TME in bladder cancer (Figs. 5B, S7A, Table S12).