TFRC and anemia: The elevated sTfR and sTfR/log ferritin in the P group have been previously reported as good biomarker of iron deficiency anemia even during inflammatory condition31.The anemia notified by reduction of plasma ferritin and the increase of sTfR and sTfR/log ferritin in PD model in the present research might occur due to disturbance in iron distribution, transport, storage and circulation in PD as reported previously7.