NRF2, Gadd45b, IRF7, and UNC93B1 exert their protective actions during infection.[246, 247, 248] For instance, Hu HL et al.[247] find that the subcellular localization of Gadd45b (a host factor) can generate a great influence on the HSV‐1 reactivation state in latently infected primary neurons. This evidence concerns the gene GADD45B and infection.